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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d77271c92e21e0673c520f30d8170ef4ca63ea2b53ba2db8063603d23bbf12' 
  AND token = 'ru4WvMErQQhRFXyUrHYnW3a2xi5Pfh2TBmg+LakEiEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}