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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17277b85bbb85e6b0a6ff74de7e168b4a362e2e16125bf2fef68f1ad1fe65ed1' 
  AND token = 'j3rjkff15aT+uIb/0PRPP7ugoAJ48fuVDyHLWjPO7GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}