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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895ceff455876b05194d8cf506776a1c3ab3f7d221ae2d18ce6a322ee7f9267e' 
  AND token = 'E0QrDGEb1r045gHNMaMpBzTUcA8s9+b8wbnE4WAZWoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}