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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f33fcee06c9b4fc36faed46a23c5fbffbfd441adeb1cdecf273bb8195135dc4' 
  AND token = 'Cu5xIZLKS3n+LFqCBEIGp0Q+O1Lr6xPRBbj8MNfM82g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}