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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11aa0e37f9569f912f4de86274d99e24e86e045c81c4373859bf93644f242222' 
  AND token = 'kuz3MggPcHsyKsfuU2noB8zVbj458vAhROJuQ2A72a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}