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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2239451f5a5d8d1c7e98ffd8e9eeb55246af831d433e1807135a7e3d7c535d3' 
  AND token = 'c4D2QAvwon+zmzJ90lYHLylUqoPiEt9v2WtKj3+3lvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}