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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e0b2325f5810add9f2496083bebd55ad7a9b04b79e3c3bf4f30ee4394151ba' 
  AND token = 'G+Y3gMwG72yEIGHNLvcq17DBWLFCxoNkteUk14hNsek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}