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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e0c6b0f9326786265bc16b3c02a361c89c92b9fb178076c26063df6f4e7818' 
  AND token = 'xbT0ttsVECSRX3M1Kgq10XWqRPyiWLzlV+iXVMmjgVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}