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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148dc125556763f3175c0a4214e3f8f9b2d34f8f3cad14dd1378f5f927ad24ae' 
  AND token = 'UzB8pmQQZ33MA8yOKvQj63xyD1lxCLr8Dtu2WCh9KZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}