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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d985367ad77beab7c99733f656d5423698857053995dfe5515d669c3623099' 
  AND token = 'KMpAaesAEmEqxvVjaEDmwcrFRVVDL4vgvq7Lob75Dms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}