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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce013889ec1e33e79fb625f7e65c5c3ac37394fe09f10511c7ec33b950099ec' 
  AND token = 'UUepwlRs2SbYIvX6QUNKXWGKC96aOOOw0N4f7GG3yEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}