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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa3ad93ccee1c8690e850d5466bc3f4c581595dbb04e8d41fad6d397eebd271' 
  AND token = 'mw8v/8uwHHzNMImFXmzwLqXnbVATI2iiTYSB8ZgwanA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}