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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95aa45a8beb3fc21d7908c4ffbea41c492a7f83cd3e6bc0d3844eda19e7b9988' 
  AND token = 'RmLUM1M3iUcc6tcoig/WBWJ1leY7GLwDRHB5V+I20Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}