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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aeb8403ced268509ba699810afce8b38344b0da2e61916718dbd4f9ed6a32c5' 
  AND token = 'PgXA1E/fAF4A7CHfeOUbYFpeXoJlzmWw4saBwqNpWIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}