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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718296fc1e41ef3cb206287d6163b68f421906aafe66819a79b31d6d2100de72' 
  AND token = 'GBlE8sVHqa48bU7V9YPMP6DxBCo+5sPchL8ZmJtFU+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}