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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8598b35e68e713c336df980521dde38ace3ab85db8cbac545456b75fedfce0f3' 
  AND token = 'z9Iyz/m6rm34dlScMNyWBG+ZQe5b7N+oBPkktd+0b3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}