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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e917de3b446faf9cd9332c0c2b131c3ae616a6f69a1f5a282da599a21d44abde' 
  AND token = 'tEk5Sj0zp3/jmc+sJqY8yHPDz0WuJVcHqAcr6ksOJ74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}