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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb6291bf887be0386be2b0dec2981c94a9f21d2b817177c53a7b5e549a84c7b2' 
  AND token = 'AOwBlSLMHq6E6pIDro8uhaIaLp/lvauMhB6wL0BnQz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}