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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea8117e9372e43c1f15bbcb93b6837d925b6e23c9e8981ed79ac48b0161fbf2' 
  AND token = 'GkhUW5PVK3fcQOnmDNGQ9O0oYZghQ7oaWAibgvqExPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}