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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5da8d79078104bf781b328a160c4088b3a75b5f9f91a7f2fd39a86d24c2c6f' 
  AND token = 'wQSpJxqpRrq6VyrQjZXQwEbR9u6u42e7r/Tp80F3cg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}