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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54b75860272c5aa7013fb679eef434d9bb5c4f9dd1f00f5f713e9305dc6d81a' 
  AND token = 'dOUnp3ZX+mvFdtuwIGlJHc9etgfd2IASjDRMFR2cjPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}