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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9b80eae3c30191ab0912e083152544f89b2b3a3b6dbd0217cf407089bb6f76' 
  AND token = 'fDjKuBjJde2wm99VsJAfccEZaOYIu9qu0fV3Z7Ct/go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}