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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e77fc24fd0b08bed7fb3c970bd615f919e4327d751b28b5edd4550ae49563a82' 
  AND token = '+eCdpE/vrEnKQ2S5wvrNuuQ+Lo9tmyujjyoGmMPXrJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}