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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4866579c02aa0e4145f0d8edb8055c7008bcce5386c38f66420cdb03f32e332' 
  AND token = 'AEjjuocfvngviw/IpV546M4xWLWe7reqsUTpQLZkwkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}