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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0902e16da49e28676499dc599e2abe168d12afc8d16e0dbec1cdac53a708d5d1' 
  AND token = 'GDxkoq2WcTSDRFg76tdgwQLbJc0zUyev9RvA6JpJxJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}