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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d06689edec3f27a18cc4373fcf9a0b146e0e07d0b09254a207ebf4f88242404' 
  AND token = 'gDexzzOaZK1d0Ahp9sPO02f3QHhpPmo9cK2ODx8H10M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}