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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d703af7e199eb140d14ca6f351792ca7b2ae01c1615cf1a0c04517baa84e01' 
  AND token = 'ksbqpd9ZH9sOiFlXWfiN1jz5GC0ErfBBl6nvAZIraz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}