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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2cbdb3a0854548b9411d3c0d7bb4a80766c41b14200b7f8e4afd21ad6f6c68' 
  AND token = '526e7LwZreuhls0gtqOuY+9QyFDQadN8wyqWEDYYZxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}