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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353121300382c0d8d42ede015fff2469cb5bac433053802e72dadf1c30e0a4ff' 
  AND token = 'Z6sXIL5T7CQtWuwVRAOvIYQY2TlGTmgSdgtC+ilb8r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}