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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8002805c80c4aa0386c98bdf8e41a7247dbccd0e8c35e6039e1c5191200b9d' 
  AND token = 'sYOC56/DSNK9Y2JVHeXmk7hGpOqK8y1tFvVz8/0awKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}