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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a57a398e7a6f4e18431d01668ec168a11fcbb2e1f08509d6f1ddadbff1e567' 
  AND token = 'HBJOk8/ytsaRtXREOTS/cL9egs675XPSiFj2TuWkIoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}