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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a727d8a2d8e86e2b96469c47c838abe197dca82e6b201eaba2bff9c391ee59ec' 
  AND token = 'khOex91zlJKd9gwJr4NI7vHdy81+YkI4wK4TYH3hu+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}