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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d9b52935a085daadde93c1095df2db1f15902f0dea76a7ad3ec745b816462a' 
  AND token = 'nNagKvPEeaqBOUrpOVQfy5hdfylVnptY1HRbky/mIYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}