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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5d604ad908d32b8fc846ff406f8e3b5f63760e458ce16021534bc21e6dd3da' 
  AND token = 'SkrGtaS53IqVrKoaA6zhf7j/QBbIYEHZuSp6OISjRgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}