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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6258936278adaf10081730bd74e208f965e41f99012e52ce9b86f81470f7c16' 
  AND token = 'Ls2eOz421YtB9w1YyS3Yp11SYQ+jU799GoGAB1jPxIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}