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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f2129decea7b8c0b94ed545fdcd1749dcb445dffa3240c2d5f2f3333870a900' 
  AND token = 'Uuww7odkWG9GDjqE4+BXqyFAkhi8+rdk2wBqyDUBQ2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}