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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd189ec11abc9780ca1d53cbebcee52a59e7df3b2caeb714905c4be9868c051e' 
  AND token = 'k44vYFh9xlOlqt3PdIyfX3r3M5I8CtZlHhPPrDQVW2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}