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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7a0aed84f015c89fd4a3992a15c012a92aa393d59c5744c61bc904fe8e4346' 
  AND token = 'Zhc7O9HYbFaawGMX6LzQZmgT/R84kCbgSdqQzSCFA8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}