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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c07366d379c2d89d88595dbc989a6b42b0b399ebb3592068ad4f27eec0ae2a4' 
  AND token = 'XFC7ZgUOA3cQnP7xD5Ytq63NDwxxWvNOiNRPyfxN+aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}