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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce0c0764c5d63be3654ae1f65fbf520aefe7da4b26552af5c0d7e59de312eda' 
  AND token = 'XpXYSqoyXmwqmu7tmx8bIFYwcbvs+v8XDouDbMr+zdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}