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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fcd90833f720590973e33fa275326be2e55a78e61283c4a7d42e216d143b67e' 
  AND token = 'VlreuAGTMmyTodxa4f4P6XTNNg4pH851TIG19wGHnDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}