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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a863acc78354050b05369b9a17604dd2dc382ed0f753de0cc5a5ee09d6f9b66' 
  AND token = 'UOYl9/LyfPpWXQcy59fT3iNpS63wwfkdv774W3bz9Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}