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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4012554d1fba001fa1d3a3b902871c2cd0ea56c18500c8b4964202f009e328aa' 
  AND token = 'Qp0FzR4wM8/ykfaO57wdEaELxhRcRZlYOLLEEhCq6LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}