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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661f8b8129084926db730735dcc91587ec6c5cc5dbf50ed5e4d05a6f26b14300' 
  AND token = 'UDo+KmWNbn9ZNTK6NMGOKfB5xhJwgAH8FMHXd9/SQuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}