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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50299ba8d5107d9e5946355496d19b9fa01cb74ad4cd0ddd4c522020ec2bb276' 
  AND token = 't3fWY2NcajL5XUAsPox+sjoPEZ0zM3CC5W8KS+BtTQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}