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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7cdf8765b1079460d7a89eb345bd53e77dfe2186ee891a01aff17c0603b1da6' 
  AND token = 'Ux54nehhw0b57rG8GSW38GAOl9LQ60TI0yg56ershT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}