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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa37510cebd2dfcad33e142ef0806b6b21e1ccbf2d88d2a482db45e02f048a7' 
  AND token = 'mHkA1dXIBb0JjhoawLopINxHEbC0VRqf5SUbS0reIp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}