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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78101df45294e787d0b419690406144b8ba52b546a62d0e760c930daf2df99b' 
  AND token = 'UgoCp4QZ+F95JP2dCCn1nAwJZejwB62qRkV3fcXs9u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}