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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd0d1b6df20221d70eb13a398a75c818d48aa7323a593e1f3a3c92082a75a42' 
  AND token = 'LF8KJwd+V5EVy44/d9Z9VAYZ+2SmaXQDVNVdC5LD7SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}