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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbf9832ec37e56f04efbfaa49db12fa24f5f8eefa7b6424bf84d72e09a38224' 
  AND token = 'VSZK5PiM8TIlzEM3yanrTkeYcPiad9Q/vtipi0qi5yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}